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Two major scientific papers published in Science and Cell (pdf) unveil a proven way to generate patient-matched human pluripotent stem cells without human cloning, and without the use of human embryos or human or animal eggs. Research groups in Wisconsin and Japan have generated "induced pluripotent state" (iPS) cells with the properties of human embryonic stem cells by direct reprogramming of adult cells. News piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells Nature, March 1, 2009 Do we still need embryos and cloning? Answering Common Claims about induced pluripotent stem cells 59k Adobe Acrobat Document Stem Cell Vindication - By Charles Krauthammer The Washington Post Stem-Cell Breakthrough Wall Street Journal The End of the Stem-Cell Wars The Weekly Standard A stem cell 'milestone' Los Angeles Times , November 20, 2007 Cell News Opens Door To Drug Discovery Forbes, November 20, 2007 Stem cells without embryos: skin cells transformed Reuters, November 20, 2007 New Stem Cell Method Could Ease Ethical Concerns The New York Times, November 20, 2007 'Milestone' stem cell advance reported CNN, November 20, 2007 The Future Is Now National Review Online , November 20, 2007 Researchers Create Stem Cells Without Destroying Embryos Wall Street Journal, November 20, 2007 Stem cell breakthrough uses no embryos Seattle Post-Intelligencer , November 20, 2007 Reprogramming Somatic Cells Towards Pluripotency by Defined Factors Science, November 2007 Summary of results on induced pluripotent state cells 23k Adobe Acrobat Document BACKGROUND In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state Nature, June 2007 Directly Reprogrammed Fibroblasts Show Global Epigenetic Remodeling and Widespread Tissue Contribution - Cell Stem Cell, June 2007 A Transcriptional Logic for Nuclear Reprogramming Cell, August 2006 Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors - Cell, August 2006 How Direct Cell Reprogramming Works Westchester Institute
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